A Labour MP is facing a vote of no confidence from local party members who accuse her of “continuously criticising” Jeremy Corbyn.
Luciana Berger has spoken out over the party’s handling of anti-Semitism and its stance on Brexit.
She has been backed by former Labour leader Ed Miliband.
But shadow chancellor John McDonnell said she should reject claims she supported a “breakaway party” to show members she was “sticking with Labour”.
Ms Berger said she would be not be “distracted from fighting for the interests of my constituents”.
An extraordinary meeting has been called in the Liverpool Wavertree constituency next week to discuss two no confidence motions.
Such votes carry no official force within the Labour Party but local activists could hold a “trigger ballot”, where sitting Labour MPs can be forced to compete for selection as a candidate against all-comers, ahead of the next general election.
Ms Berger has been the target of online abuse and had a police escort at last year’s Labour Party conference following death threats.
Earlier this week, she joined other MPs at a meeting of the Parliamentary Labour Party calling for details on the party’s efforts to tackle anti-Semitism to be released.
In a statement, Ms Berger said she believed her constituents would judge her on her record and skills in representing them in Parliament.
She reiterated her “long held view that Brexit will be a disaster for the people of Liverpool Wavertree and the wider country”, saying she would “not shy away from standing up” for her Remain-voting constituency.
And she said she had made “no secret that, as a Jewish woman representing a city with a Jewish community, I have been deeply disturbed by the lack of response from Jeremy Corbyn as party leader and many in the wider leadership of the party to the anti-Semitism that stains our party”.
Ms Berger added: “Nothing will deter me from exposing anti-Semitism wherever it festers, including in the Labour Party where it is being wilfully ignored.”
‘Further relentless abuse’
Former Labour leader Ed Miliband tweeted that “she should be supported not undermined by everyone throughout our party”, while prominent backbencher Yvette Cooper praised Ms Berger’s campaigning and said she had her “solidarity”.
Her colleague Jess Phillips also tweeted, warning that the move “means a night of further relentless abuse, anti-Semitism and violent threats to her and her family”.
However, speaking to BBC Radio 4’s Today programme, Mr McDonnell said the motion came about because Ms Berger is “associated” with rumours of a new centrist party being formed.
“[The motion] is an expression of views,” he said.
“If people are doing that because Luciana has stood up against [anti-Semitism] that is completely wrong.
“But from what I have seen on social media, it looks as though what has happened is Luciana has been in the media associated with a breakaway party and hasn’t been clear that she rejects that.”
He condemned a Facebook post from one of the local Labour members calling Ms Berger a “disruptive Zionist”, saying it was “completely wrong”.
But the shadow chancellor said: “My advice to Luciana is just tell people you are not supporting a breakaway party, you are sticking with the Labour Party, you are not jumping ship.
“And my advice to the Labour Party members there is if there are differences of opinion there, get together, talk about it and see how you can support the campaign alongside your local MP.”
Labour MPs have taken to Twitter to criticise Mr McDonnell’s response.
Chuka Umunna tweeted: “So a victim of outrageous racism in @UKLabour must promise she will not walk because of that racism and then this can all go away.
“How about demanding her CLP [Constituency Labour Party] treats her with the respect she deserves. How about the party deals with that racism. Words fail me. Totally unacceptable.”
While Wes Streeting tweeted: “The only thing Luciana isn’t ‘clear’ about is whether she is still welcome in the Labour Party after years of anti-Semitic abuse.”
Meanwhile, Labour activists from the “Another Europe is Possible” group are targeting the constituencies of MPs who broke the whip and voted with the government over Theresa May’s Brexit deal, calling it a “moment of reckoning”.
Seven Labour MPs backed an amendment supported by the government calling for “alternative arrangements” to the backstop element of Mrs May’s plan – which aims to avoid a hard border returning between Northern Ireland and Ireland.
And a total of 26 MPs either abstained or voted against an amendment by Yvette Cooper, that was backed by the Labour leadership, which would have allowed for an extension of Article 50 – the mechanism seeing the UK leave the EU on 29 March – by up to nine months, with the aim of avoiding a no deal.
The left wing group, founded last summer, will campaign in around 30 constituencies to “apply pressure” to the MPs to vote against Mrs May’s deal.
Gordon Watson, the Labour deputy leader of Rotherham Council, warned that the rebels could end up facing de-selection if they don’t vote the deal down, adding: “Failing to vote against the Tory deal is essentially propping up a government that is wrecking our communities. People are running out of patience.”